Shon Stump asked 5 years ago
My child will be 3 years old next week.  Tonight for the first time he began complaining of leg pain.  I know there is a connection between MCADD and leg pain but I am uncertain why this would be the first time he would complain of it.  He is a very active child and we have had on hospitalization in his life.  Needless to say I am concerned.  Is there some dumbed down research I can find that explains the link between the leg pain and MCADD

1 Answers
INFORM Physician answered 5 years ago
Shon, Unfortunately there really isn’t any published research on this area. We typically don’t think of MCAD deficiency as having the same kind of muscle symptoms as we see in the long chain disorders, but it has certainly been reported, even to the extent of episodes of rhabdomyolysis. It probably has to do with impaired energy production in a time of higher need, including times of rapid growth, increased activity, or illness. It’s best to contact your metabolic team for an evaluation and look for any underlying cause that can be treated. If not, then providing increased fluids and usable calories (complex carbohydrates and protein) with shorter periods of fasting may help. Again, work with your metabolic team for changes that are appropriate and specific to your child. Hope this helps. Dr. Vockley