DWQA QuestionsCategory: QuestionsMix of solcarb with MCT pre-workouts?
D. asked 2 years ago
I am a patient living with cpt2 deficiency.
My doctor would like me to try a mix of solcarb with mct before my workouts to see if that would help, before I try dojolvi.
I am already taking mct (in sachets, 10g/dose) 3 times a day. I would usually take 1 sachet of mct and some kind of carb (like a banana) right before I exercise, and eat some type of carb with a little bit of protein after I exercise. I would still experience symptoms from time to time, because of stress, exercise, extreme temperatures, etc.
My nutritionist explained to me the rationale between the suggestion for me to mix mct with solcarb: solcarb is a complex carb, so it could give me energy for longer. However, when I look it up, it says that solcarb is composed of maltodextrin, and its glycemic index is higher than table sugar, ranging from 106 to 136 (so I would probably get a short, big spike of glucose in my bloodstream). Also, it’s in the form of powder (https://www.specialtyfoodshop.ca/products/specialized-nutritional-needs/energy-boosting/modulesfoodsother/solcarb) so I’m guessing that it’s digested quicker than a banana. Also,  although a banana contains sugar, it also contains fiber and its glycemic index is around 56 (for a ripe banana)… half the glycemic index of solcarb!
I am a bit confused. I just wanted to get another opinion.
Thank you in advance!
Keith McIntire
replied 2 years ago

You are correct solcarb is a rapid absorbed carbohydrate often used to provide a quick source of glucose.
1. I do recommend an MCT carbohydrate mix 20 min to 1 hour before exercise. Most sports nutrition RDs recommend .5 -1 gm carbohydrate per kg of body weight and 10g of MCT is plenty. The big difference between a banana and solcarb is how fast it is absorbed. Yes, solcarb will be absorbed quickly with a rise in blood glucose. I would eat the banana perhaps 30 min before exercise and take the solcarb closer to exercise – say 10-20 min before.
2. The plan of carbs with protein after exercise is also good. Sports Nutrition RDs recommend a 4:1 ratio of carbohydrate to protein about 30-45 min after exercise.

I gave a talk about exercise physiology at the MitoAction meeting that breaks down a lot of these Sports Nutrition recommendations that might be helpful. It was recorded and is available on the MitoAction website I believe.

It sounds like this regimen works some of the time and does not under some conditions such as high temperatures or added stress. I’m not sure varying the carbohydrate source will change this. It might be more effective to identify what factors (such as high temperatures) negatively impact your ability to exercise and avoid those triggers or modify your workout when you have added stress.

Would dojolvi provide some added benefit? We observed a lower heart rate with C7 or dojolvi during moderate exercise over MCT in our randomized clinical trial. Subject perceived the exercise to be easier or less stressful. Trying dojolvi with carbohydrate before exercise is a good idea to see if that improves your ability to workout.

In the end, the perfect nutrition support regimen may not always prevent rhabdomyolysis or other symptoms of CPT2 deficiency. We are still trying to understand the underlying cause of rhabdomyolysis and develop more effective therapies for LC-FAODs. Thanks for your question, Melanie Gillingham PhD, RD

Keith McIntire
replied 2 years ago

PLEASE watch this video: Exercise Physiology & FAODs- Dr. Melanie Gillingham / https://www.youtube.com/watch?v=vbU3Ss6YGSk&list=PLTrGsiiotyLf-fCLITVSG6VBQ9UvGxv5H&index=13