FOR DISTINGUISHED ACHIEVEMENT IN RESEARCH PRESENTED BY THE SCIENTIFIC BOARD OF INFORM IN SPONSORSHIP WITH NESTLE HEALTHSCIENCE
Anuradha Karunanidhi is a Senior Lab Manager and Research V specialist with a background in Pharmaceutical Sciences and Chemical Engineering with 20+ years of experience spanning research and teaching. She holds a master’s degree in chemical engineering from Indian Institute of Technology, Chennai, India. She has been part of the Dr. Vockley lab for past 14 years. She plays a major role in the ongoing projects involving mitochondrial fatty acid oxidation disorders including ACAD9, CPT II, MCAD, VLCAD, LCAHD, and TFP deficiencies by using her expertise and techniques in designing, developing, screening and optimizing in vitro patients cell culture models to evaluate efficacy of pharmaceutical compounds to remedy the underlying biochemical abnormalities using an array of biomarkers including the effect on production of Reactive Oxygen Species (ROS), immune imaging on cells and tissues using confocal microscopy, and ATP production levels by high-throughput 96 well plate luminescence assay. Additionally, she has independently trained, identified and custom developed the assays needed for studying key cellular functions, glycolysis, mitochondrial respiration, and the bioenergetic profiling of live patient cells in real time using state-of-art Agilent Seahorse Bioanalyzer instrument. She has trained postdocs, visiting scholars, medical fellows, graduate, and undergraduate students. Her experimental results, and those from other lab members she has taught, have been integrated into multiple published manuscripts and two funded NIH R01 grants.
Prior to joining Dr. Vockley lab, she had also worked with other renowned scientists:
- Dr. Steven Little, Dept of Chemical Engineering, Swanson School of Engineering, University of Pittsburgh
- Dr. Jeffrey Hollinger, Bone Tissue engineering center, CMU
During her tenure she has been nominated for multiple staff recognition and chancellor’s award.