Cell Model Created to Better Understand Vision Loss in Form of LCFAOD

Researchers have created cell line models to better study the mechanisms of progressive chorioretinopathy in a form of long chain fatty acid oxidation disorder (LCFAOD).

Tiffany DeVine, PhD
Credit: INFORM

Tiffany DeVine, PhD, postdoctoral researcher at the Gillingham lab at Oregon Health and Science University in Portland, presented data demonstrating that the Gillingham lab has been successful in creating a retinal pigment epithelium (RPE) model of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD) from induced pluripotent stem cells (iPSCs).