Cell Model Created to Better Understand Vision Loss in Form of LCFAOD

Researchers have created cell line models to better study the mechanisms of progressive chorioretinopathy in a form of long chain fatty acid oxidation disorder (LCFAOD).

Tiffany DeVine, PhD, postdoctoral researcher at the Gillingham lab at Oregon Health and Science University in Portland, presented data demonstrating that the Gillingham lab has been successful in creating a retinal pigment epithelium (RPE) model of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD) from induced pluripotent stem cells (iPSCs).